abstract：:Sevoflurane is widely used in adult and pediatric patients during clinical surgeries. Although studies have shown that exposure to sevoflurane impairs solfactory memory after an operation, the neuropathological changes underlying this effect are not clear. This study detected the effect of sevoflurane exposure on the ...

journal_title：Frontiers in neuroanatomy

authors： Yang J,Chen J,Cai G,Lu R,Sun T,Luo T,Wu S,Ling S

更新日期：2016-06-24 00:00:00

abstract：:A60, the mouse monoclonal antibody against the neuronal nuclear protein (NeuN), is the most widely used neuronal marker in neuroscience research and neuropathological assays. Previous studies identified fragments of A60-immunoprecipitated protein as Synapsin I (Syn I), suggesting the antibody will demonstrate cross im...

journal_title：Frontiers in neuroanatomy

authors： Mao S,Xiong G,Zhang L,Dong H,Liu B,Cohen NA,Cohen AS

更新日期：2016-05-13 00:00:00

abstract：:Biological impacts of light beyond vision, i.e., non-visual functions of light, signify the need to better understand light detection (or photoreception) systems in vertebrates. Photopigments, which comprise light-absorbing chromophores bound to a variety of G-protein coupled receptor opsins, are responsible for visua...

journal_title：Frontiers in neuroanatomy

authors： Hang CY,Kitahashi T,Parhar IS

更新日期：2016-04-27 00:00:00

abstract：:A subset of monoamine neurons releases glutamate as a cotransmitter due to presence of the vesicular glutamate transporters VGLUT2 or VGLUT3. In addition to mediating vesicular loading of glutamate, it has been proposed that VGLUT3 enhances serotonin (5-HT) vesicular loading by the vesicular monoamine transporter (VMA...

journal_title：Frontiers in neuroanatomy

authors： Voisin AN,Mnie-Filali O,Giguère N,Fortin GM,Vigneault E,El Mestikawy S,Descarries L,Trudeau LÉ

更新日期：2016-04-12 00:00:00

abstract：:The neural circuits involved in mediating complex behaviors are being rapidly elucidated using various newly developed and powerful anatomical and molecular techniques, providing insights into the neural basis for anxiety disorders, depression, addiction, and dysfunctional social behaviors. Many of these behaviors and...

journal_title：Frontiers in neuroanatomy

authors： Santos FN,Pereira CW,Sánchez-Pérez AM,Otero-García M,Ma S,Gundlach AL,Olucha-Bordonau FE

更新日期：2016-04-07 00:00:00

abstract：:Imaging entire mouse brains at submicron resolution has historically been a challenging undertaking and largely confined to the province of dedicated atlasing initiatives. This has limited systematic investigations into important areas of neuroscience, such as neural circuits, brain mapping and neurodegeneration. In t...

journal_title：Frontiers in neuroanatomy

authors： Amato SP,Pan F,Schwartz J,Ragan TM

更新日期：2016-03-22 00:00:00

abstract：:The last 140 years have seen considerable advances in knowledge of central nervous system tumors. However, the main tumor types had already been described during the early years of the twentieth century. The studies of Dr. Pío del Río Hortega have been ones of the most exhaustive histology and cytology-based studies o...

journal_title：Frontiers in neuroanatomy

authors： Ramon Y Cajal Agüeras S

更新日期：2016-03-01 00:00:00

abstract：:The distribution of vitamin D-dependent calcium-binding protein (28 kDa calbindin) was investigated in cat lumbar and sacral spinal cord segments (L1-S3). We observed specific multi-dimensional distributions over the spinal segments for small immunopositive cells in Rexed laminae II-III and medium-to-large cells of va...

journal_title：Frontiers in neuroanatomy

authors： Merkulyeva N,Veshchitskii A,Makarov F,Gerasimenko Y,Musienko P

更新日期：2016-01-28 00:00:00

abstract：:Diffusion tensor imaging (DTI) and tractography offer the unique possibility to visualize the developing white matter macroanatomy of the human fetal brain in vivo and in utero and are currently under investigation for their potential use in the diagnosis of developmental pathologies of the human central nervous syste...

journal_title：Frontiers in neuroanatomy

authors： Mitter C,Jakab A,Brugger PC,Ricken G,Gruber GM,Bettelheim D,Scharrer A,Langs G,Hainfellner JA,Prayer D,Kasprian G

更新日期：2015-12-24 00:00:00

abstract：:[This corrects the article on p. 99 in vol. 9, PMID: 26300740.]. ...

journal_title：Frontiers in neuroanatomy

authors： Hernández LF,Redgrave P,Obeso JA

更新日期：2015-11-17 00:00:00

abstract：:Perinatal asphyxia (PA) is an obstetric complication that strongly affects the CNS. The endocannabinoid system (ECS) is a lipid transmitter system involved in several physiological processes including synaptic plasticity, neurogenesis, memory, and mood. Endocannabinoids, and other acylethanolamides (AEs) without endoc...

journal_title：Frontiers in neuroanatomy

authors： Blanco E,Galeano P,Holubiec MI,Romero JI,Logica T,Rivera P,Pavón FJ,Suarez J,Capani F,Rodríguez de Fonseca F

更新日期：2015-11-03 00:00:00

abstract：:The striatum and the subthalamic nucleus (STN) are the main entry doors for extrinsic inputs to reach the basal ganglia (BG) circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei. There is anatomical, functional and neurochemical evidence that glutamatergic ...

journal_title：Frontiers in neuroanatomy

authors： Villalba RM,Mathai A,Smith Y

更新日期：2015-09-25 00:00:00

abstract：:Previous developmental studies of the thalamus (alar part of the diencephalic prosomere p2) have defined the molecular basis for the acquisition of the thalamic competence (preparttening), the subsequent formation of the secondary organizer in the zona limitans intrathalamica, and the early specification of two antero...

journal_title：Frontiers in neuroanatomy

authors： Bandín S,Morona R,González A

更新日期：2015-08-10 00:00:00

abstract：:Dopamine (DA) modulates the effects of amino acid neurotransmitters (AANs), including GABA and glutamate, in motor, visual, olfactory, and reward systems (Hnasko et al., 2010; Stuber et al., 2010; Hnasko and Edwards, 2012). The results suggest that DA may play a similar modulatory role in the auditory pathways. Previo...

journal_title：Frontiers in neuroanatomy

authors： Fyk-Kolodziej BE,Shimano T,Gafoor D,Mirza N,Griffith RD,Gong TW,Holt AG

更新日期：2015-07-22 00:00:00

abstract：:Blue tits (Cyanistes coeruleus) are songbirds, used as model animals in numerous studies covering a wide field of research. Nevertheless, the distribution of neuropeptides in the brain of this avian species remains largely unknown. Here we present some of the first results on distribution of Vasotocine (AVT) and Vasoa...

journal_title：Frontiers in neuroanatomy

authors： Montagnese CM,Székely T,Csillag A,Zachar G

更新日期：2015-07-14 00:00:00

abstract：:Adult born neurons in the hippocampus show species-specific differences in their numbers, the pace of their maturation and their spatial distribution. Here, we present quantitative data on adult hippocampal neurogenesis in a New World primate, the common marmoset (Callithrix jacchus) that demonstrate parts of the line...

journal_title：Frontiers in neuroanatomy

authors： Amrein I,Nosswitz M,Slomianka L,van Dijk RM,Engler S,Klaus F,Raineteau O,Azim K

更新日期：2015-06-29 00:00:00

abstract：:Standard stereotaxic reference systems play a key role in human brain studies. Stereotaxic coordinate systems have also been developed for experimental animals including non-human primates, dogs, and rodents. However, they are lacking for other species being relevant in experimental neuroscience including sheep. Here,...

journal_title：Frontiers in neuroanatomy

authors： Nitzsche B,Frey S,Collins LD,Seeger J,Lobsien D,Dreyer A,Kirsten H,Stoffel MH,Fonov VS,Boltze J

更新日期：2015-06-04 00:00:00

abstract：:Lateralization of motor control refers to the ability to produce pure unilateral or asymmetric movements. It is required for a variety of coordinated activities, including skilled bimanual tasks and locomotion. Here we discuss the neuroanatomical substrates and pathophysiological underpinnings of lateralized motor out...

journal_title：Frontiers in neuroanatomy

authors： Welniarz Q,Dusart I,Gallea C,Roze E

更新日期：2015-06-02 00:00:00

abstract：:Analyses of mice carrying a deletion of the pan-neurotrophin receptor p75NTR have allowed identifying p75NTR as an important structural regulator of the hippocampus. Most of the previous analyses were done using p75NTR (ExIII) knockout mice which still express the short isoform of p75NTR. To scrutinize the role of p75...

journal_title：Frontiers in neuroanatomy

authors： Poser R,Dokter M,von Bohlen Und Halbach V,Berger SM,Busch R,Baldus M,Unsicker K,von Bohlen Und Halbach O

更新日期：2015-05-27 00:00:00

abstract：:Pathways arising from the ventral tegmental area (VTA) release dopamine and other neurotransmitters during the expectation and achievement of reward, and are regarded as central links of the brain networks that create drive, pleasure, and addiction. While the global pattern of VTA projections is well-known, the actual...

journal_title：Frontiers in neuroanatomy

authors： Aransay A,Rodríguez-López C,García-Amado M,Clascá F,Prensa L

更新日期：2015-05-19 00:00:00

abstract：:When does adult hippocampal neurogenesis begin? We describe the development of the neurogenic niche in the subgranular zone (SGZ) of the hippocampal dentate gyrus. We did so from the perspective of the situation in the adult. Ontogeny of the dentate gyrus is complex and results in an ectopic neurogenic niche that life...

journal_title：Frontiers in neuroanatomy

authors： Nicola Z,Fabel K,Kempermann G

更新日期：2015-05-07 00:00:00

abstract：:Dendrite and dendritic spine formation are crucial for proper brain function. DISC1-binding zinc finger protein (DBZ) was first identified as a Disrupted-In-Schizophrenia1 (DISC1) binding partner. DBZ is highly expressed in the cerebral cortex of developing and adult rodents and is involved in neurite formation, cell ...

journal_title：Frontiers in neuroanatomy

authors： Koyama Y,Hattori T,Nishida T,Hori O,Tohyama M

更新日期：2015-04-30 00:00:00

abstract：:The hypothalamus has been a central topic in neuroanatomy because of its important physiological functions, but its mature organization remains elusive. Deciphering its embryonic and adult organization is crucial in an evolutionary approach of the organization of the vertebrate forebrain. Here we studied the molecular...

journal_title：Frontiers in neuroanatomy

authors： Santos-Durán GN,Menuet A,Lagadec R,Mayeur H,Ferreiro-Galve S,Mazan S,Rodríguez-Moldes I,Candal E

更新日期：2015-04-08 00:00:00

abstract：:The olfactory bulb (OB) of mammals receives cholinergic afferents from the horizontal limb of the diagonal band of Broca (HDB). At present, the synaptic connectivity of the cholinergic axons on the circuits of the OB has only been investigated in the rat. In this report, we analyze the synaptic connectivity of the cho...

journal_title：Frontiers in neuroanatomy

authors： Liberia T,Blasco-Ibáñez JM,Nácher J,Varea E,Lanciego JL,Crespo C

更新日期：2015-03-17 00:00:00

abstract：:Dendritic spines are key components of a variety of microcircuits and they represent the majority of postsynaptic targets of glutamatergic axon terminals in the brain. The present article will focus on the discovery of dendritic spines, which was possible thanks to the application of the Golgi technique to the study o...

journal_title：Frontiers in neuroanatomy

authors： DeFelipe J

更新日期：2015-03-05 00:00:00

abstract：:Immunohistochemistry (IHC) is a valuable method for identifying discrete neurochemical molecules by the interaction of target antigens with validated antibodies tagged with a visible label (e.g., peroxidase). We have developed an immunostaining method that is highly sensitive in detection of neurochemical antigens. Ou...

journal_title：Frontiers in neuroanatomy

authors： Goto S,Morigaki R,Okita S,Nagahiro S,Kaji R

更新日期：2015-03-03 00:00:00

abstract：:In mammalian cerebrum there exist two distinct types of interneurons expressing nitric oxide synthase (NOS). Type I neurons are large in size and exhibit heavy nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) histochemical reaction, while type II cells are small with light NADPH-d reactivity. The time ...

journal_title：Frontiers in neuroanatomy

authors： Liu C,Yang Y,Hu X,Li JM,Zhang XM,Cai Y,Li Z,Yan XX

更新日期：2015-02-16 00:00:00

abstract：:Most studies in mammals and birds have demonstrated common patterns of hypothalamic development highlighted by the combination of developmental regulatory genes (genoarchitecture), supporting the notion of the hypothalamus as a component of the secondary prosencephalon, topologically rostral to the diencephalon. In ou...

journal_title：Frontiers in neuroanatomy

authors： Domínguez L,González A,Moreno N

更新日期：2015-02-03 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the global population over 65 years of age. A hallmark feature of PD is the degeneration of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc) and the consequent striatal DA deficiency. Yet, the pathogenesis of PD re...

journal_title：Frontiers in neuroanatomy

authors： Blesa J,Przedborski S

更新日期：2014-12-15 00:00:00

abstract：:Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has been hypothesized to confine biochemical and electric signals within...

journal_title：Frontiers in neuroanatomy

authors： Adrian M,Kusters R,Wierenga CJ,Storm C,Hoogenraad CC,Kapitein LC

更新日期：2014-12-04 00:00:00

abstract：:Rafael Lorente de Nó, the youngest of Santiago Ramón y Cajal disciples, was one of the last Century's more influential researches in neuroscience. This assay highlights two fundamental contributions of Rafael Lorente de Nó to neurobiology: the intrinsic organization of the mammalian cerebral cortex and the basic physi...

journal_title：Frontiers in neuroanatomy

authors： Larriva-Sahd JA

更新日期：2014-12-03 00:00:00

abstract：:Despite many structural and functional aspects of the brain organization have been extensively studied in neuroscience, we are still far from a clear understanding of the intricate structure-function interactions occurring in the multi-layered brain architecture, where billions of different neurons are involved. Altho...

journal_title：Frontiers in neuroanatomy

authors： Ullo S,Nieus TR,Sona D,Maccione A,Berdondini L,Murino V

更新日期：2014-11-20 00:00:00

abstract：:How does the size of the glial and neuronal cells that compose brain tissue vary across brain structures and species? Our previous studies indicate that average neuronal size is highly variable, while average glial cell size is more constant. Measuring whole cell sizes in vivo, however, is a daunting task. Here we use...

journal_title：Frontiers in neuroanatomy

authors： Mota B,Herculano-Houzel S

更新日期：2014-11-12 00:00:00

abstract：:Why do neurons have dendritic spines? This question-the heart of what Yuste calls "the spine problem"-presupposes that why-questions of this sort have scientific answers: that empirical findings can favor or count against claims about why neurons have spines. Here we show how such questions can receive empirical answe...

journal_title：Frontiers in neuroanatomy

authors： Malanowski S,Craver CF

更新日期：2014-09-10 00:00:00

abstract：:Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

journal_title：Frontiers in neuroanatomy

authors： Herculano-Houzel S,Manger PR,Kaas JH

更新日期：2014-08-11 00:00:00

abstract：:Experiments in several species have identified direct projections to the medial geniculate nucleus (MG) from cells in subcollicular auditory nuclei. Moreover, many cochlear nucleus cells that project to the MG send collateral projections to the inferior colliculus (IC) (Schofield et al., 2014). We conducted three expe...

journal_title：Frontiers in neuroanatomy

authors： Schofield BR,Mellott JG,Motts SD

更新日期：2014-07-18 00:00:00

abstract：:Accurate 3D reconstruction of neurons is vital for applications linking anatomy and physiology. Reconstructions are typically created using Neurolucida after biocytin histology (BH). An alternative inexpensive and fast method is to use freeware such as Neuromantic to reconstruct from fluorescence imaging (FI) stacks a...

journal_title：Frontiers in neuroanatomy

authors： Blackman AV,Grabuschnig S,Legenstein R,Sjöström PJ

更新日期：2014-07-11 00:00:00

abstract：:Cortical calretinin (CR)-expressing interneurons represent a heterogeneous subpopulation of about 10-30% of GABAergic interneurons, which altogether total ca. 12-20% of all cortical neurons. In the rodent neocortex, CR cells display different somatodendritic morphologies ranging from bipolar to multipolar but the bipo...

journal_title：Frontiers in neuroanatomy

authors： Cauli B,Zhou X,Tricoire L,Toussay X,Staiger JF

更新日期：2014-06-24 00:00:00

abstract：:Cortical networks are shaped by sensory experience and are most susceptible to modifications during critical periods characterized by enhanced plasticity at the structural and functional level. A system particularly well-studied in this context is the mammalian visual system. Plasticity has been documented for the som...

journal_title：Frontiers in neuroanatomy

authors： Gutzmann A,Ergül N,Grossmann R,Schultz C,Wahle P,Engelhardt M

更新日期：2014-03-11 00:00:00

abstract：:Gaze changes involving the eyes and head are orchestrated by brainstem gaze centers found within the superior colliculus (SC), paramedian pontine reticular formation (PPRF), and medullary reticular formation (MdRF). The mesencephalic reticular formation (MRF) also plays a role in gaze. It receives a major input from t...

journal_title：Frontiers in neuroanatomy

authors： Perkins E,May PJ,Warren S

更新日期：2014-01-10 00:00:00